Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949046 | 0.89 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EALDH1A1MAPT | |
| SCHEMBL9189037 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8949247 | 0.86 | KDM1A (0.44) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8519571 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL8949226 | 0.84 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL8949254 | 0.83 | ITGB3 (0.39) | ITGB3ITGA2BALOX15 | |
| SCHEMBL8949209 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL7381654 | 0.80 | UBE2T (0.51) | ITGB3ITGA2BALOX15 | |
| Hydrochloric Acid SCHEMBL8949404 | 0.80 | KDM1A (0.43) | ITGB3ITGA2B | |
| SCHEMBL9278118 | 0.78 | ITGB3 (0.37) | ITGB3ITGA2BALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |