Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949142 | 0.99 | PRSS1 (0.44) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL8949309 | 0.92 | ITGB3 (0.48) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL8949271 | 0.89 | HTR2B (0.41) | PRSS1PRSS2PRSS3ST14F10 | |
| Hydrochloric Acid SCHEMBL8949289 | 0.85 | ITGB3 (0.45) | PRSS1PRSS2PRSS3ST14F10 | |
| Hydrochloric Acid SCHEMBL8949069 | 0.83 | ITGB3 (0.43) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL9186836 | 0.81 | ITGB3 (0.51) | PRSS1PRSS2PRSS3ST14F10 | |
| Hydrochloric Acid SCHEMBL8949011 | 0.80 | ITGB3 (0.40) | PRSS1PRSS2PRSS3ST14F10 | |
| Hydrochloric Acid SCHEMBL8949340 | 0.80 | ITGB3 (0.40) | PRSS1PRSS2PRSS3ST14F10 | |
| Hydrochloric Acid SCHEMBL8409916 | 0.80 | ITGB3 (0.50) | PRSS1PRSS2PRSS3ST14F10 | |
| Hydrochloric Acid SCHEMBL8949325 | 0.80 | ITGB3 (0.45) | PRSS1PRSS2PRSS3ST14F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | claimed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | claimed |
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |