Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | GMPS | P49915 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 6/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | NADK | O95544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495963 | 0.88 | PI4KA (0.46) | ADORA2AGMPSADORA3AHCYSLC28A1 | |
| SCHEMBL934614 | 0.85 | ADORA3 (0.47) | ADORA2AGMPSADORA3AHCYTAS1R3 | |
| SCHEMBL30216733 | 0.84 | EHMT1 (0.45) | ADORA2AGMPSADORA3AHCYTAS1R3 | |
| SCHEMBL8677295 | 0.77 | ADORA2A (0.48) | ADORA2AGMPSADORA3AHCYSLC28A1 | |
| SCHEMBL30139991 | 0.77 | ADORA2A (0.48) | ADORA2AGMPSADORA3AHCYSLC28A1 | |
| SCHEMBL998090 | 0.76 | PI4KA (0.48) | ADORA2AGMPSADORA3AHCYSLC28A1 | |
| SCHEMBL4751168 | 0.75 | ADORA2A (0.46) | ADORA2AGMPSADORA3AHCYSLC28A1 | |
| SCHEMBL4830361 | 0.75 | ADORA2A (0.46) | ADORA2AGMPSADORA3AHCYTAS1R3 | |
| SCHEMBL6650344 | 0.75 | ADORA2A (0.46) | ADORA2AGMPSADORA3AHCYSLC28A1 | |
| SCHEMBL6935380 | 0.75 | PI4KA (0.48) | ADORA2AGMPSADORA3AHCYSLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697351-A | Pharmaceutical composition for chemical inhibition of TGS1 as a treatment method for telomerase | 罗马大学 | 2023-02-03 | — | — | CN | claimed |
| US-4948783-A | ORALLY ADMINISTERING ADENOSINE OR DERIVATIVE | KABUSHIKI KAISYA ADVANCE KAIHATSU KENKYUJO (JP) | 1990-08-14 | — | — | US | claimed |
| JP-8183737-A | — | — | None | — | — | JP | disclosed |
| JP-H08183737-A | ALCOHOL ABSORPTION INHIBITOR | ADVANCE CO LTD | 1996-07-16 | — | — | JP | disclosed |
| EP-0191561-B1 | ANTICARIOGENIC OR ANTIPERIODONTITIC AGENT | KABUSHIKI KAISYA ADVANCE (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4948783-A | ORALLY ADMINISTERING ADENOSINE OR DERIVATIVE | KABUSHIKI KAISYA ADVANCE KAIHATSU KENKYUJO (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0191561-A2 | Anticariogenic or antiperiodontitic agent | KABUSHIKI KAISYA ADVANCE (JP) | 1986-08-20 | — | — | EP | disclosed |