Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.70 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.44 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949625 | 0.99 | LTB4R (0.71) | LTB4RLTB4R2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8949530 | 0.98 | LTB4R (0.70) | LTB4RLTB4R2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8949584 | 0.91 | LTB4R (0.69) | LTB4RLTB4R2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8949534 | 0.91 | LTB4R (0.84) | LTB4RLTB4R2KDM4EMEN1ALDH1A1 | |
| SCHEMBL11862585 | 0.81 | TP53 (0.69) | LTB4RKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11859295 | 0.79 | KMT2A (0.69) | LTB4RKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL8949612 | 0.77 | LTB4R (0.80) | LTB4RLTB4R2TP53 | |
| SCHEMBL10454274 | 0.77 | TP53 (0.62) | LTB4RKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11860605 | 0.77 | KDM4E (0.72) | LTB4RKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL8949619 | 0.76 | LTB4R (0.78) | LTB4RLTB4R2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |