SCHEMBL8949593

SCHEMBL8949593

CC(c1ccccc1)P(=O)(O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
ANPEP P15144 1/20 0.46
ACP3 P15309 9/20 0.46
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 1/20 0.40
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232549 0.82 SRC (0.60) SRCANPEPACP3
SCHEMBL6030734 0.82 SRC (0.54) SRCANPEPACP3ALDH1A1CA2
SCHEMBL28543474 0.80 SRC (0.58) SRCANPEPACP3
SCHEMBL11775225 0.78 SRC (0.50) SRCANPEPACP3ALDH1A1
Potassium Ion SCHEMBL10975285 0.78 SRC (0.50) SRCANPEPACP3ALDH1A1CA2
SCHEMBL28467116 0.77 SRC (0.46) SRCANPEPACP3ALDH1A1POLB
SCHEMBL18893729 0.75 SRC (0.47) SRCANPEPACP3ALDH1A1POLB
SCHEMBL7746267 0.75 SRC (0.47) SRCANPEPACP3POLB
Phosphoric Acid SCHEMBL28355238 0.75 SRC (0.56) SRCANPEPACP3ALDH1A1CA2
Isopropylbenzene SCHEMBL11472092 0.75 SRC (0.56) SRCANPEPACP3CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5574024-A Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism EBETINO FRANK H (US) 1996-11-12 US disclosed
EP-0298553-B1 METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM Norwich Eaton Pharmaceuticals, Inc. (US) 1992-01-15 EP disclosed
EP-0298553-A1 Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism Norwich Eaton Pharmaceuticals, Inc. (US) 1989-01-11 EP disclosed