Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 9/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232549 | 0.82 | SRC (0.60) | SRCACP3ANPEP | |
| SCHEMBL6030734 | 0.82 | SRC (0.54) | SRCACP3ANPEPALDH1A1CA2 | |
| SCHEMBL28543474 | 0.80 | SRC (0.58) | SRCACP3ANPEP | |
| SCHEMBL11775225 | 0.78 | SRC (0.50) | SRCACP3ANPEPALDH1A1 | |
| SCHEMBL8949593 | 0.78 | SRC (0.50) | SRCACP3ANPEPALDH1A1CA2 | |
| Isopropylbenzene SCHEMBL38664331 | 0.77 | SRC (0.43) | SRCACP3ALDH1A1POLB | |
| SCHEMBL28467116 | 0.77 | SRC (0.46) | SRCACP3ANPEPALDH1A1POLB | |
| Potassium Ion SCHEMBL10975645 | 0.76 | ACP3 (0.49) | SRCACP3ANPEPPOLB | |
| SCHEMBL18893729 | 0.75 | SRC (0.47) | SRCACP3ANPEPALDH1A1POLB | |
| SCHEMBL7746267 | 0.75 | SRC (0.47) | SRCACP3ANPEPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074296-B1 | FLAME-RESISTANT RESINOUS COMPOSITION CONTAINING A POLYCARBONATE, A HEMI-ESTER OF PHOSPHONIC ACID AND OPTIONALLY OTHER ADDITIVES AND/OR FILLERS, AND HEMI-ESTERS OF PHOSPHONIC ACID | ATO CHIMIE, Société Anonyme dite: (FR) | 1985-11-06 | — | — | EP | claimed |