Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949786 | 0.93 | GCGR (0.47) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9744058 | 0.88 | GCGR (0.43) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9482135 | 0.88 | GCGR (0.44) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9482140 | 0.88 | GCGR (0.44) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL7561153 | 0.85 | ESR1 (0.62) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8973684 | 0.85 | ESR1 (0.62) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8949909 | 0.85 | GCGR (0.42) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9380517 | 0.85 | RXRA (0.47) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8949603 | 0.84 | GCGR (0.58) | GCGR | |
| SCHEMBL10587512 | 0.83 | GCGR (0.40) | GCGRESR1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502057-A | Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5470982-A | Disubstituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| EP-0325129-B1 | Disubstituted pyridines | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-4968689-A | Certain 2,6-diisopropyl-4-(4-fluoro-phenyl)-3,5-bis-dimethyl-3',5'-dihydroxy-hept-6-enoate-pyridine derivatives useful for treating lipoproteinaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0325129-A2 | Disubstituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |