SCHEMBL8949684

SCHEMBL8949684

CCCCCCCCc1cc(OCCO)ccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.60
HPSE Q9Y251 1/20 0.54
TSHR P16473 2/20 0.54
TP53 P04637 1/20 0.54
RARB P10826 3/20 0.53
CNR2 P34972 3/20 0.53
CNR1 P21554 1/20 0.53
PLA2G4B P0C869 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28555724 0.92 PTPN11 (0.53) PTPN11HPSETSHRTP53RARB
SCHEMBL1022635 0.89 PTPN11 (0.55) PTPN11TSHRTP53RARBPLA2G4B
SCHEMBL15344614 0.86 PTPN11 (0.54) PTPN11HPSETSHRTP53RARB
SCHEMBL8974262 0.86 PTPN11 (0.64) PTPN11TSHRTP53RARBPLA2G4B
SCHEMBL4518420 0.85 PTPN11 (0.61) PTPN11TSHRTP53RARBPLA2G4B
SCHEMBL8925473 0.83 PPARA (0.58) PTPN11HPSETSHRTP53
SCHEMBL28832371 0.83 PPARA (0.58) PTPN11HPSETSHRTP53
SCHEMBL28177026 0.83 PPARA (0.58) PTPN11HPSETSHRTP53
SCHEMBL28832253 0.83 PPARA (0.58) PTPN11HPSETSHRTP53
SCHEMBL28082706 0.83 PPARA (0.58) PTPN11HPSETSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480761-A CHROMOGENIC PHOTOGRAPHIC ELEMENTS WITH DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1996-01-02 US disclosed