Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064238 | 0.97 | PTPN11 (0.59) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL15344562 | 0.90 | KMT2A (0.59) | PTPN11TP53TSHRPLA2G4BRARB | |
| SCHEMBL8179881 | 0.89 | PTPN11 (0.70) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL16836638 | 0.89 | PTPN11 (0.70) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL7272804 | 0.89 | PTPN11 (0.70) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL7820620 | 0.88 | PTPN11 (0.64) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL5492191 | 0.88 | PTPN11 (0.64) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL416135 | 0.87 | PTPN11 (0.57) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL8085899 | 0.87 | PTPN11 (0.68) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL1376266 | 0.86 | PTPN11 (0.63) | PTPN11TP53TSHRPLA2G4BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702668-A1 | DISCOTIC COMPOUNDS FOR USE IN LIQUID CRYSTAL MIXTURES | The Secretary of St. for Def. in her Britannic Maj. Governm of the Un. Kingdom of Gr. Brit. and N. Ireland (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029263-A1 | DISCOTIC COMPOUNDS FOR USE IN LIQUID CRYSTAL MIXTURES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1994-12-22 | — | — | WO | disclosed |