⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988890 | 0.83 | — | — | |
| SCHEMBL2291549 | 0.83 | — | — | |
| SCHEMBL815761 | 0.79 | — | — | |
| SCHEMBL11067197 | 0.71 | — | — | |
| SCHEMBL13597972 | 0.69 | — | — | |
| SCHEMBL13854212 | 0.69 | NLRP3 (0.34) | — | |
| SCHEMBL9273950 | 0.69 | — | — | |
| SCHEMBL15681388 | 0.69 | — | — | |
| SCHEMBL16437708 | 0.69 | — | — | |
| SCHEMBL8914631 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147894-A1 | PREPARATION METHOD FOR GLUFOSINATE AMMONIUM | 利尔化学股份有限公司 | 2021-07-29 | — | — | WO | claimed |
| CN-111393473-A | Preparation method of ethyl methyl ethyl phosphinate | 利尔化学股份有限公司 | 2020-07-10 | — | — | CN | claimed |
| WO-2024051120-A1 | PREPARATION METHOD FOR 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTYRIC ACID | 浙江新安化工集团股份有限公司 | 2024-03-14 | — | — | WO | disclosed |
| WO-2024051119-A1 | PREPARATION METHOD FOR 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTYRIC ACID | 浙江新安化工集团股份有限公司 | 2024-03-14 | — | — | WO | disclosed |
| WO-2022264043-A1 | ONE POT PROCESS FOR PREPARATION OF A CHIRAL AMINO ACID | UPL LIMITED (IN) | 2022-12-22 | — | — | WO | disclosed |
| EP-3909962-A1 | METHOD OF PRODUCING L-GLUFOSINATE | CJ Cheiljedang Corporation (KR) | 2021-11-17 | — | — | EP | disclosed |
| WO-2021147894-A1 | PREPARATION METHOD FOR GLUFOSINATE AMMONIUM | 利尔化学股份有限公司 | 2021-07-29 | — | — | WO | disclosed |
| WO-2021143712-A1 | METHOD FOR PREPARING L-GLUFOSINATE-AMMONIUM INTERMEDIATE | 利尔化学股份有限公司 | 2021-07-22 | — | — | WO | disclosed |
| WO-2020145514-A1 | METHOD OF PRODUCING L-GLUFOSINATE | 씨제이제일제당(주) | 2020-07-16 | — | — | WO | disclosed |
| CN-111393473-A | Preparation method of ethyl methyl ethyl phosphinate | 利尔化学股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| EP-3356376-B1 | METHOD FOR THE PREPARATION OF PHOSPHINATES | BASF SE (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-20140336373-A1 | NOVEL COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES | CISBIO BIOASSAYS (FR) | 2014-11-13 | — | — | US | disclosed |
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0550478-A1 | SUBSTITUTED 2 IMIDAZOLONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| EP-0356128-B1 | 3-(AMINOPROPYL)METHYL PHOSPHINIC ACID AS A THERAPEUTIC AGENT | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992004331-A1 | SUBSTITUTED 2 IMIDAZOLONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| WO-1990001936-A1 | 3-(AMINOPROPYL)METHYL PHOSPHINIC ACID AS A THERAPEUTIC AGENT AND INTERMEDIATES IN ITS SYNTHESIS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-03-08 | — | — | WO | disclosed |
| EP-0356128-A2 | 3-(Aminopropyl)methyl phosphinic acid as a therapeutic agent | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-02-28 | — | — | EP | disclosed |
| EP-0298553-A1 | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-01-11 | — | — | EP | disclosed |