⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949978 | 0.96 | — | — | |
| SCHEMBL12192415 | 0.78 | — | — | |
| SCHEMBL434706 | 0.76 | — | — | |
| SCHEMBL28170809 | 0.76 | — | — | |
| SCHEMBL23712986 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3033587 | 0.73 | — | — | |
| Hydrogen Sulfide SCHEMBL8742077 | 0.73 | — | — | |
| SCHEMBL28173392 | 0.70 | — | — | |
| SCHEMBL8604497 | 0.70 | — | — | |
| SCHEMBL611038 | 0.67 | TAS2R38 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498636-B1 | Cosmetic composition | ZENECA LTD (GB) | 1995-09-06 | — | — | EP | claimed |
| EP-0500352-A1 | Biocidal compositions containing oxy-phosphorous compounds to enhance solubility | ZENECA LIMITED (GB) | 1992-08-26 | — | — | EP | claimed |
| EP-0392648-A1 | Metal complexes, the preparation thereof and use as biocides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-17 | — | — | EP | claimed |
| JP-61109795-A | — | — | None | — | — | JP | disclosed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-9151874-B2 | Near-infrared reflective film, method for manufacturing near-infrared reflective film, and near-infrared reflector | KONICA MINOLTA HOLDINGS, INC. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-8664233-B2 | Substituted 5H-pyrimido[5,4-B]indoles, method for the production thereof and use thereof for treating non-solid malignant tumors of the blood-producing system | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2014-03-04 | — | — | US | disclosed |
| US-8664233-B2 | Substituted 5H-pyrimido[5,4-B]indoles, method for the production thereof and use thereof for treating non-solid malignant tumors of the blood-producing system | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20130100523-A1 | NEAR-INFRARED REFLECTIVE FILM, METHOD FOR MANUFACTURING NEAR-INFRARED REFLECTIVE FILM, AND NEAR-INFRARED REFLECTOR | KONICA MINOLTA HOLDINGS, INC. (JP) | 2013-04-25 | — | — | US | disclosed |
| EP-2104675-B1 | SUBSTITUTED 5H-PYRIMIDOL[5,4-B]INDOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR TREATING NON-SOLID MALIGNANT TUMORS OF THE BLOOD-PRODUCING SYSTEM | MEDICINES CO LEIPZIG GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-20110021511-A1 | SUBSTITUTED 5H-PYRIMIDO[5,4-B]INDOLES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING NON-SOLID MALIGNANT TUMORS OF THE BLOOD-PRODUCING SYSTEM | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| EP-0498636-A1 | Cosmetic composition | ZENECA LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |
| EP-0392648-A1 | Metal complexes, the preparation thereof and use as biocides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-17 | — | — | EP | disclosed |
| JP-S61109795-A | PHENYLTHIOL PHOSPHONIC ACID DERIVATIVE, ITS PREPARATION AND INSECTICIDE, ACARICIDE AND NEMATOCIDE | HOKKO CHEM IND CO LTD | 1986-05-28 | — | — | JP | disclosed |
| EP-0051990-B1 | BIOLOGICALLY ACTIVE HETEROBICYCLIC HYDROXIMIDATES AND THIOLHYDROXIMIDATES AND CARBAMATE ESTER DERIVATIVES THEREOF | SDS BIOTECH CORPORATION (US) | 1986-01-02 | — | — | EP | disclosed |
| US-4548929-A | Insecticidal and nematocidal heterobicyclic hydroximinates, thiohydroximidates, and carbamate esters, composition, and method of use thereof | SDS BIOTECH CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| US-4424213-A | PESTICIDES | SDS BIOTECH CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| WO-1982001650-A1 | BIOLOGICALLY ACTIVE HETEROBICYCLIC HYDROXIMIDATES AND THIOLHYDROXIMIDATES AND CARBAMATE ESTER DERIVATIVES THEREOF | DIAMOND SHAMROCK CORP (US) | 1982-05-27 | — | — | WO | disclosed |
| EP-0051990-A1 | Biologically active heterobicyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof | SDS BIOTECH CORPORATION (US) | 1982-05-19 | — | — | EP | disclosed |
| US-4096166-A | Process for the preparation of carbamates of N-hydroxythioimidates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-20 | — | — | US | disclosed |