Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.38 |
| ▸ | PGK2 | P07205 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727813 | 0.73 | PGK1 (0.41) | PGK1PGK2PTPN1 | |
| SCHEMBL641074 | 0.72 | — | — | |
| SCHEMBL26085065 | 0.69 | — | — | |
| SCHEMBL1954678 | 0.69 | — | — | |
| SCHEMBL1542130 | 0.69 | PGK1 (0.42) | PGK1PGK2PTPN1 | |
| Phosphoric Acid SCHEMBL2586140 | 0.68 | PGK1 (0.47) | PGK1PGK2PTPN1 | |
| SCHEMBL8728056 | 0.67 | — | — | |
| SCHEMBL13493760 | 0.67 | — | — | |
| SCHEMBL16445123 | 0.67 | PGK1 (0.40) | PGK1PGK2PTPN1 | |
| Phosphoric Acid SCHEMBL31173152 | 0.62 | PGK1 (0.42) | PGK1PGK2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0298553-A1 | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-01-11 | — | — | EP | disclosed |