Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL8949815 | 1.00 | CA2 (0.50) | CA2TSHRCYP2C19FDPSMMP1 | |
| SCHEMBL7790209 | 0.88 | — | — | |
| Methane SCHEMBL10582767 | 0.84 | — | — | |
| Ethane SCHEMBL8949825 | 0.84 | CA2 (0.58) | CA2TSHRFDPSMMP2MMP3 | |
| Methylamine SCHEMBL9161531 | 0.80 | CA2 (0.54) | CA2TSHRFDPSLMNA | |
| Cyclopentene SCHEMBL8950071 | 0.78 | CA2 (0.37) | CA2 | |
| Cyclohexene SCHEMBL8949757 | 0.78 | CA2 (0.37) | CA2 | |
| Cyclohexane SCHEMBL25174142 | 0.74 | TSHR (0.42) | CA2TSHRCYP2C19FDPSMMP1 | |
| Cyclohexane SCHEMBL521319 | 0.74 | TSHR (0.42) | CA2TSHRCYP2C19FDPSMMP1 | |
| Cycloheptane SCHEMBL7041097 | 0.74 | TSHR (0.42) | CA2TSHRCYP2C19FDPSMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0298553-A1 | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-01-11 | — | — | EP | disclosed |