SCHEMBL8950197

SCHEMBL8950197

COc1ccc(CO)c([N+](=O)[O-])c1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
POLB P06746 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
TRPV1 Q8NER1 1/20 0.44
PKM P14618 1/20 0.44
HTT P42858 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
TTR P02766 1/20 0.40
HPGD P15428 1/20 0.40
MAPT P10636 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215343 0.87 TDP1 (0.46) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL18138425 0.85 TDP1 (0.45) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL5964869 0.84 KDM4E (0.44) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL5964706 0.84 TDP1 (0.44) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL1882600 0.84 TDP1 (0.47) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL11748681 0.84 KDM4E (0.44) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL4101467 0.83 ALDH1A1 (0.51) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL29787159 0.81 TRPV1 (0.44) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL16033385 0.81 ALDH1A1 (0.42) KDM4EPOLBTDP1L3MBTL1CTDSP1
SCHEMBL5373510 0.81 KDM4E (0.45) KDM4EPOLBTDP1L3MBTL1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113979895-B Self-degradable polymer with controllable precise sequence and preparation method and application thereof 中国科学技术大学 2023-03-24 CN disclosed
CN-113979895-A Self-degradable polymer with controllable precise sequence and preparation method and application thereof 中国科学技术大学 2022-01-28 CN disclosed
US-9546364-B2 Synthetic lariat RNA for RNA interference CARNEGIE MELLON UNIVERSITY (US) 2017-01-17 US disclosed
US-20140273216-A1 Synthetic Lariat RNA for RNA Interference Camegie Mellon University (US) 2014-09-18 US disclosed
US-5508141-A AQUEOUS ACIDIC PHOTORESIST EMULSION CONTAINING RESIN, POSITIVE-ACTING PHOTOACTIVE FUNCTIONALITY, ACID, OXIDIZING AGENT, SURFACTANT W. R. GRACE & CO.-CONN. (US) 1996-04-16 US disclosed
CN-1030739-C Method for selectively coating metal surface, method for forming circuit pattern from metal surface and photosensitive emulsion used therefor GRACE W R & CO (US) 1996-01-17 CN disclosed
EP-0468002-A4 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES GRACE W R & CO (US) 1995-08-09 EP disclosed
US-5232815-A Corrosion resistance W. R. GRACE & CO.-CONN. (US) 1993-08-03 US disclosed
EP-0518453-A1 A method of making electrical circuit traces W.R. Grace & Co.-Conn. (US) 1992-12-16 EP disclosed
EP-0468002-A1 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES W.R. GRACE & CO.-CONN. (US) 1992-01-29 EP disclosed
CN-1054836-A Automatic deposition emulsion and the method for the metal surface being carried out selective protection with this emulsion GRACE W R & CO (US) 1991-09-25 CN disclosed
WO-1991008840-A1 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES W.R. GRACE & CO.-CONN. (US) 1991-06-27 WO disclosed
CN-1036276-A Make the method for erect image and negative-appearing image with the static main leaf of photo-hardening DU PONT (US) 1989-10-11 CN disclosed
US-4859551-A Process for preparing positive and negative images using photohardenable electrostatic master E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-08-22 US disclosed
EP-0315121-A2 Process for preparing positive and negative images using photohardenable electrostatic master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-10 EP disclosed
US-4632900-A Process for the production of images after electrodeposition of positive photoresist on electrically conductive surface CIBA-GEIGY CORPORATION (US) 1986-12-30 US disclosed
US-4269933-A PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-26 US disclosed
US-4198242-A Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed