Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.71 |
| ▸ | CA4 | P22748 | 3/20 | 0.71 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950227 | 0.85 | CA2 (0.65) | CA2CA4CA1CA9CA12 | |
| SCHEMBL29941334 | 0.84 | CA2 (1.00) | CA2CA4ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8950360 | 0.83 | CA2 (0.98) | CA2CA4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8950266 | 0.80 | CA2 (0.46) | CA2CA4ALDH1A1HPGDALOX15 | |
| SCHEMBL9057333 | 0.78 | CA2 (0.47) | CA2CA4CA1CA9ALDH1A1 | |
| SCHEMBL8950230 | 0.76 | CA2 (0.45) | CA2CA4CA1CA9CA12 | |
| Hydrochloric Acid SCHEMBL8950276 | 0.75 | CA2 (0.53) | CA2CA4CA1CA9CA12 | |
| SCHEMBL8950476 | 0.75 | CA2 (0.45) | CA2CA4CA1CA9CA12 | |
| SCHEMBL8950275 | 0.74 | CA2 (0.53) | CA2CA4CA1CA9CA12 | |
| Hydrochloric Acid SCHEMBL8950342 | 0.74 | CA2 (0.84) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |