Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530876 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL5608433 | 0.79 | EPHX1 (0.54) | ALDH1A1EPHX1HIF1ACYP3A4TRPA1 | |
| SCHEMBL9264539 | 0.79 | ALDH1A1 (0.74) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 | |
| SCHEMBL19645458 | 0.78 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 | |
| SCHEMBL8620 | 0.78 | — | — | |
| SCHEMBL15492354 | 0.78 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 | |
| SCHEMBL13174777 | 0.78 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 | |
| SCHEMBL1164134 | 0.78 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 | |
| SCHEMBL12513617 | 0.78 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 | |
| SCHEMBL12338087 | 0.78 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595364-B1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-07-24 | — | — | EP | disclosed |
| US-5439940-A | Sedatives, anticonvulsants; analgesics, cardiotonic agents, antiinflammatory agents | EGIS GYOGYSZERGYAR RT. (HU) | 1995-08-08 | — | — | US | disclosed |
| EP-0595364-A1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-05-04 | — | — | EP | disclosed |