Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 17/20 | 0.54 |
| ▸ | GABRD | O14764 | 17/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 17/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 17/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 17/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 17/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 17/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 17/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 17/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 17/20 | 0.54 |
| ▸ | GABRE | P78334 | 17/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 17/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 17/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 17/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 17/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950625 | 0.86 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950621 | 0.86 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950889 | 0.83 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950896 | 0.83 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950645 | 0.81 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950691 | 0.80 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950572 | 0.77 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9677369 | 0.75 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950458 | 0.74 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950509 | 0.74 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294229-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-12-02 | — | — | EP | claimed |
| US-5502073-A | INSECTICIDES OR ANTHELMINTICS | THE WELLCOME FOUNDATION (GB) | 1996-03-26 | — | — | US | disclosed |