Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950412 | 0.83 | CA2 (0.38) | CA2CA4CA1CA12CA3 | |
| SCHEMBL8950332 | 0.82 | CA2 (0.43) | CA2CA4CA1CA12CA3 | |
| Hydrochloric Acid SCHEMBL8950276 | 0.77 | CA2 (0.53) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9057841 | 0.76 | CA2 (0.36) | CA2 | |
| Hydrochloric Acid SCHEMBL8950237 | 0.76 | CA2 (0.62) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950563 | 0.75 | CA2 (0.49) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8950331 | 0.75 | CA2 (0.62) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950523 | 0.71 | CA2 (0.45) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9058810 | 0.70 | CA2 (0.32) | CA2 | |
| SCHEMBL8950230 | 0.69 | CA2 (0.45) | CA2CA4CA1CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |