SCHEMBL8952134

SCHEMBL8952134

CCOC=CC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952132 1.00
SCHEMBL28064599 0.79
SCHEMBL4894741 0.79 ALDH1A1 (0.32)
SCHEMBL4894736 0.79 ALDH1A1 (0.32)
SCHEMBL29628870 0.77
SCHEMBL17811626 0.74
SCHEMBL19667932 0.74
SCHEMBL19667931 0.74
SCHEMBL16247241 0.74
SCHEMBL24511860 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114556656-A Electrolyte solution for lithium ion battery cells 霍尼韦尔国际公司 2022-05-27 CN claimed
EP-3997753-A1 ELECTROLYTE SOLUTION FOR A LITHIUM ION CELL Honeywell International Inc. (US) 2022-05-18 EP claimed
CN-114556656-A Electrolyte solution for lithium ion battery cells 霍尼韦尔国际公司 2022-05-27 CN disclosed
EP-3997753-A1 ELECTROLYTE SOLUTION FOR A LITHIUM ION CELL Honeywell International Inc. (US) 2022-05-18 EP disclosed
US-5514816-A REACTION OF DIFLUOROBENZO-1,3-DIOXOLE WITH METAL COMPOUNDS FOR INSECTICIDES CIBA-GEIGY CORPORATION (US) 1996-05-07 US disclosed
US-5496848-A Process for the preparation of substituted difluorobenzo-1,3-dioxoles CIBA-GEIGY CORPORATION (US) 1996-03-05 US disclosed
US-5493032-A INSECTICIDES, MICROBIOCIDES CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
EP-0333658-B1 Process for the preparation of substituted difluorbenzo-1,3-dioxoles CIBA GEIGY AG (CH) 1995-07-26 EP disclosed
US-5420301-A Process for the preparation of substituted difluorobenzo-1,3-dioxoles CIBA-GEIGY CORPORATION (US) 1995-05-30 US disclosed
US-5281718-A Reacting in one pot reaction 2,2-difluorobenzodioxole with an organometal compound or metal to form 4-metallo-2,2-difluorobenzodioxole, reacting with unsaturated nitrile, then with isocyanide CIBA-GEIGY CORPORATION (US) 1994-01-25 US disclosed
US-5194628-A Reacting metallo-difluorobenzodioxole with unsaturated nitrile and then with sulfonylmethyl isocyanide CIBA-GEIGY CORPORATION (US) 1993-03-16 US disclosed
EP-0333658-A2 Process for the preparation of substituted difluorbenzo-1,3-dioxoles CIBA-GEIGY AG (CH) 1989-09-20 EP disclosed