Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803807 | 0.97 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL8952273 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL8952196 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL8802653 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL9118286 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL8952264 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL9027303 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL8952343 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL7201245 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL8952239 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697873-A4 | — | — | 1996-04-03 | — | — | EP | claimed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | claimed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | claimed |
| EP-0697873-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |