Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952170 | 0.99 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952374 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952238 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952332 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPK1HSD17B10KDM4E | |
| SCHEMBL8952243 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952322 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL515834 | 0.73 | KDM4E (0.54) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL6948261 | 0.72 | HSD17B10 (0.55) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL19013585 | 0.71 | KDM4E (0.55) | ALDH1A1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL8952239 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662834-A4 | NOVEL EPOXIDE-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0697873-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0662834-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994006431-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-03-31 | — | — | WO | disclosed |