Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449773 | 1.00 | BACE1 (0.64) | BACE1MAOAMAOBKDM4EACP1 | |
| SCHEMBL12401857 | 0.81 | KDM4E (0.47) | BACE1MAOAMAOBKDM4EUSP2 | |
| SCHEMBL10914959 | 0.80 | AR (0.44) | BACE1KDM4EHTTARCYP2C9 | |
| SCHEMBL3300391 | 0.79 | BACE1 (0.66) | BACE1KDM4EACP1HTTC1R | |
| SCHEMBL2334850 | 0.79 | BACE1 (0.53) | BACE1MAOAMAOBKDM4EACP1 | |
| SCHEMBL17433836 | 0.79 | KDM4E (0.49) | BACE1MAOAMAOBKDM4EUSP2 | |
| SCHEMBL2335294 | 0.78 | BACE1 (0.64) | BACE1ACP1C1RARELANE | |
| SCHEMBL4116547 | 0.78 | BACE1 (1.00) | BACE1MAOAKDM4EACP1HTT | |
| SCHEMBL12803449 | 0.78 | BACE1 (0.46) | BACE1MAOAMAOBACP1C1R | |
| SCHEMBL19117639 | 0.78 | BACE1 (0.64) | BACE1KDM4EACP1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126090-A | Iridium complex photosensitizer and preparation method and application thereof | 南京工业大学 | 2024-06-04 | — | — | CN | claimed |
| CN-118146151-A | 4-Trifluoromethyl substituted quinoline and quinazoline compound and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2024-06-07 | — | — | CN | disclosed |
| CN-118126090-A | Iridium complex photosensitizer and preparation method and application thereof | 南京工业大学 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024085525-A1 | IRIDIUM COMPLEX, PHOTOSENSITIZER, AND COMPOSITION FOR PHOTODYNAMIC THERAPY | 울산과학기술원 | 2024-04-25 | — | — | WO | disclosed |
| US-20230158005-A1 | Substituted Azole Dione Compounds with Antiviral Activity | STEMLINE THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |
| EP-3567035-B1 | N-SUBSTITUTED 2,5-DIOXO-AZOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | CANBAS CO LTD (JP) | 2022-06-01 | — | — | EP | disclosed |
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | CORNELL UNIVERSITY (US) | 2022-02-15 | — | — | US | disclosed |
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | RAQUALIA PHARMA INC. (JP) | 2021-10-26 | — | — | US | disclosed |
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-20030236259-A1 | Novel aryl- and heteroarylpiperazines | HIGH POINT PHARMACEUTICALS, LLC | 2003-12-25 | — | — | US | disclosed |
| WO-2003066604-A2 | NOVEL ARYL- AND HETEROARYLPIPERAZINES | NOVO NORDISK A/S (DK) | 2003-08-14 | — | — | WO | disclosed |
| EP-0317188-B1 | Heteroaromatic enamide derivatives and their use as pesticides | ROUSSEL UCLAF (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-5114940-A | Insecticides or anthelmintics from fused ring heterocycles containing amides or thioamides | ROUSSEL-UCLAF (FR) | 1992-05-19 | — | — | US | disclosed |
| EP-0317188-A2 | Heteroaromatic enamide derivatives and their use as pesticides | ROUSSEL UCLAF (FR) | 1989-05-24 | — | — | EP | disclosed |
| EP-0152319-B1 | PROCESS FOR OBTAINING COMPOUNDS WITH AN ALKOXYACYLIDENE GROUP | RHONE-POULENC CHIMIE (FR) | 1987-07-22 | — | — | EP | disclosed |
| EP-0168305-B1 | PROCESS FOR THE STABILISATION OF ALKYL ALKOXYALKYLIDENE MALONATES | RHONE-POULENC CHIMIE (FR) | 1987-04-22 | — | — | EP | disclosed |
| EP-0168305-A1 | Process for the stabilisation of alkyl alkoxyalkylidene malonates | RHONE-POULENC CHIMIE (FR) | 1986-01-15 | — | — | EP | disclosed |
| EP-0152319-A1 | Process for obtaining compounds with an alkoxyacylidene group | RHONE-POULENC CHIMIE (FR) | 1985-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | SCN8A, SCN7A, SCN1A | BACE1 1350/4885MAOA 2088/4885MAOB 1592/4885 |
| US-20030236259-A1 | Novel aryl- and heteroarylpiperazines | HRH3, HRH2, HRH4 | BACE1 3643/4885MAOA 638/4885MAOB 646/4885 |
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | MALT1, BCL6, BCL3 | BACE1 699/4885MAOA 4302/4885MAOB 3524/4885 |
| US-20230158005-A1 | Substituted Azole Dione Compounds with Antiviral Activity | MAVS, DDX18, ZC3HAV1 | BACE1 4359/4885MAOA 2906/4885MAOB 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.