Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952568 | 0.80 | L3MBTL1 (0.43) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL8952643 | 0.79 | L3MBTL1 (0.43) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL8952594 | 0.79 | L3MBTL1 (0.43) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL8952578 | 0.74 | GAA (0.49) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL11293663 | 0.74 | L3MBTL1 (0.57) | GAAL3MBTL1HSD17B10HPGDCYP2C9 | |
| SCHEMBL5088230 | 0.72 | SMN1; SMN2 (0.45) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL515834 | 0.71 | KDM4E (0.54) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL8952569 | 0.71 | KDM4E (0.46) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL9419701 | 0.71 | L3MBTL1 (0.48) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL8952659 | 0.71 | HSD17B10 (0.49) | GAAL3MBTL1HSD17B10SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669825-A4 | HYDROXYL-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0669825-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011001-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |