Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952668 | 1.00 | ELANE (0.46) | ELANEITGB1ITGA5SMN1; SMN2KDM4E | |
| SCHEMBL5963210 | 1.00 | ELANE (0.46) | ELANEITGB1ITGA5SMN1; SMN2KDM4E | |
| SCHEMBL8952682 | 1.00 | ELANE (0.46) | ELANEITGB1ITGA5SMN1; SMN2KDM4E | |
| SCHEMBL5963742 | 0.90 | ELANE (0.44) | ELANESMN1; SMN2KDM4E | |
| SCHEMBL5964258 | 0.85 | ELANE (0.43) | ELANESMN1; SMN2 | |
| SCHEMBL5963634 | 0.85 | ELANE (0.43) | ELANESMN1; SMN2 | |
| SCHEMBL7984168 | 0.85 | ELANE (0.43) | ELANESMN1; SMN2 | |
| SCHEMBL28495663 | 0.84 | ELANE (0.49) | ELANESMN1; SMN2KDM4E | |
| SCHEMBL5964086 | 0.83 | ELANE (0.49) | ELANESMN1; SMN2KDM4E | |
| SCHEMBL5963508 | 0.82 | ELANE (0.41) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690856-A4 | — | UNIV NEW YORK (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0690856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1994-10-13 | — | — | WO | disclosed |