Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729786 | 0.90 | ELANE (0.47) | ELANEKDM4EGAATSHRMEN1 | |
| SCHEMBL1134975 | 0.89 | ELANE (0.46) | ELANETSHRSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL7732985 | 0.89 | ELANE (0.46) | ELANEKDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL5887434 | 0.89 | ELANE (0.46) | ELANETSHRSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5887440 | 0.89 | ELANE (0.46) | ELANETSHRSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5964086 | 0.89 | ELANE (0.49) | ELANEKDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL7778743 | 0.88 | ELANE (0.45) | ELANEKDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL5963742 | 0.87 | ELANE (0.44) | ELANEKDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL7772609 | 0.87 | ELANE (0.47) | ELANEKDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL5963529 | 0.87 | ELANE (0.44) | ELANEKDM4EGAATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922329-B | Process and intermediates for the preparation of water-soluble taxane derivatives | 江苏恩华络康药物研发有限公司 | 2020-11-24 | — | — | CN | disclosed |