⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953003 | 0.91 | — | — | |
| SCHEMBL8952839 | 0.89 | — | — | |
| SCHEMBL8952852 | 0.89 | — | — | |
| SCHEMBL8952940 | 0.88 | — | — | |
| SCHEMBL8952910 | 0.87 | HMGCR (0.40) | — | |
| SCHEMBL9441498 | 0.86 | CTSA (0.32) | — | |
| SCHEMBL8953284 | 0.85 | — | — | |
| SCHEMBL9562794 | 0.85 | — | — | |
| SCHEMBL8952774 | 0.85 | — | — | |
| SCHEMBL8952998 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | disclosed |