Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952835 | 0.87 | — | — | |
| SCHEMBL8952852 | 0.86 | — | — | |
| SCHEMBL9562794 | 0.85 | — | — | |
| SCHEMBL9562784 | 0.85 | — | — | |
| SCHEMBL8953003 | 0.85 | — | — | |
| SCHEMBL8952973 | 0.85 | HMGCR (0.49) | HMGCR | |
| SCHEMBL8952988 | 0.85 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9853863 | 0.83 | HMGCR (0.30) | HMGCR | |
| SCHEMBL9781040 | 0.83 | HMGCR (0.30) | HMGCR | |
| SCHEMBL8952839 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | disclosed |