Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 10/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953198 | 0.97 | FPR2 (0.37) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953275 | 0.96 | FPR2 (0.36) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953242 | 0.96 | FPR2 (0.36) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953402 | 0.96 | FPR2 (0.36) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953130 | 0.96 | FPR2 (0.36) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953556 | 0.95 | FPR2 (0.35) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953136 | 0.95 | FPR2 (0.40) | FPR2PDE4APDE4BKDM1A | |
| SCHEMBL8953752 | 0.94 | FPR2 (0.35) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953471 | 0.93 | FPR2 (0.37) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8953034 | 0.93 | KDM1A (0.39) | FPR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |