Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856061 | 1.00 | DPP4 (0.41) | DPP4DPP8CTSKELANECTSL | |
| SCHEMBL895743 | 0.87 | ELANE (0.32) | DPP4ELANECHRM2CHRM1CHRM3 | |
| SCHEMBL896532 | 0.85 | DPP4 (0.49) | DPP4 | |
| SCHEMBL6205677 | 0.84 | DPP4 (0.57) | DPP4DPP8CTSKCTSLCTSB | |
| SCHEMBL6205055 | 0.84 | DPP4 (0.57) | DPP4DPP8CTSKCTSLCTSB | |
| SCHEMBL648249 | 0.84 | DPP4 (0.57) | DPP4DPP8CTSKCTSLCTSB | |
| SCHEMBL648248 | 0.84 | DPP4 (0.57) | DPP4DPP8CTSKCTSLCTSB | |
| SCHEMBL645764 | 0.83 | DPP4 (0.58) | DPP4DPP8CTSKCTSLCTSB | |
| SCHEMBL13078897 | 0.82 | ELOVL6 (0.42) | DPP4DPP8 | |
| SCHEMBL3744361 | 0.82 | ELOVL6 (0.42) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748457-B2 | 2-amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent DPP-IV inhibitors | LUPIN LIMITED (IN) | 2014-06-10 | — | — | US | disclosed |
| US-8748457-B2 | 2-amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent DPP-IV inhibitors | LUPIN LIMITED (IN) | 2014-06-10 | — | — | US | disclosed |
| US-8748457-B2 | 2-amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent DPP-IV inhibitors | LUPIN LIMITED (IN) | 2014-06-10 | — | — | US | disclosed |
| US-20120082635-A1 | 2-AMINO-2- [8-(DIMETHYL CARBAMOYL)- 8-AZA- BICYCLO [3.2.1] OCT-3-YL]-EXO- ETHANOYL DERIVATIVES AS POTENT DPP-IV INHIBITORS | LUPIN LIMITED (IN) | 2012-04-05 | — | — | US | disclosed |
| US-20120082635-A1 | 2-AMINO-2- [8-(DIMETHYL CARBAMOYL)- 8-AZA- BICYCLO [3.2.1] OCT-3-YL]-EXO- ETHANOYL DERIVATIVES AS POTENT DPP-IV INHIBITORS | LUPIN LIMITED (IN) | 2012-04-05 | — | — | US | disclosed |
| US-20120082635-A1 | 2-AMINO-2- [8-(DIMETHYL CARBAMOYL)- 8-AZA- BICYCLO [3.2.1] OCT-3-YL]-EXO- ETHANOYL DERIVATIVES AS POTENT DPP-IV INHIBITORS | LUPIN LIMITED (IN) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082635-A1 | 2-AMINO-2- [8-(DIMETHYL CARBAMOYL)- 8-AZA- BICYCLO [3.2.1] OCT-3-YL]-EXO- ETHANOYL DERIVATIVES AS POTENT DPP-IV INHIBITORS | DPP7, DPP4, DPP8 | DPP4 2/4885DPP8 3/4885CTSK 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.