⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264026 | 1.00 | — | — | |
| SCHEMBL2158198 | 1.00 | — | — | |
| SCHEMBL7010813 | 0.75 | — | — | |
| SCHEMBL896129 | 0.75 | — | — | |
| SCHEMBL8110842 | 0.71 | — | — | |
| SCHEMBL9032301 | 0.69 | — | — | |
| SCHEMBL653175 | 0.57 | — | — | |
| SCHEMBL5160419 | 0.55 | — | — | |
| SCHEMBL5164268 | 0.55 | — | — | |
| SCHEMBL414574 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513808-A2 | FLUORINATED CYCLIC AMIDES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | Pfizer Products Inc. (US) | 2005-03-16 | — | — | EP | claimed |
| WO-2005019168-A2 | FLUORINATED LYSINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-03-03 | — | — | WO | claimed |
| US-20050043292-A1 | Fluorinated lysine derivatives as dipeptidyl peptidase IV inhibitors | PFIZER INC | 2005-02-24 | — | — | US | claimed |
| US-20040132713-A1 | Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors | PFIZER INC | 2004-07-08 | — | — | US | claimed |
| US-6710040-B1 | Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors | PFIZER INC. | 2004-03-23 | — | — | US | claimed |
| WO-2003101958-A2 | FLOURINATED CYCLIC AMIDES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-12-11 | — | — | WO | claimed |
| CN-116888124-A | Bicyclic derivatives | 礼蓝动物保健有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-4255911-A1 | BICYCLIC DERIVATIVES | Elanco Tiergesundheit AG (CH) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117783-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2022-06-09 | — | — | WO | disclosed |
| EP-3075730-B1 | AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | GENENTECH INC (US) | 2018-10-24 | — | — | EP | disclosed |
| US-20180265481-A1 | METHOD FOR PREPARATION OF CERTAIN 1,5 DISUBSTITUTED TETRAZOLES | LONZA LTD. (CH) | 2018-09-20 | — | — | US | disclosed |
| EP-3221305-B1 | METHOD FOR PREPARATION OF CERTAIN 1,5 DISUBSTITUTED TETRAZOLES | LONZA AG (CH) | 2018-03-07 | — | — | EP | disclosed |
| EP-3221305-A1 | METHOD FOR PREPARATION OF CERTAIN 1,5 DISUBSTITUTED TETRAZOLES | Lonza Ltd (CH) | 2017-09-27 | — | — | EP | disclosed |
| EP-1911350-A1 | AMIDINE COMPOUND AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 2008-04-16 | — | — | EP | disclosed |
| EP-1513808-A2 | FLUORINATED CYCLIC AMIDES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | Pfizer Products Inc. (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2005019168-A2 | FLUORINATED LYSINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043292-A1 | Fluorinated lysine derivatives as dipeptidyl peptidase IV inhibitors | PFIZER INC | 2005-02-24 | — | — | US | disclosed |
| US-20040132713-A1 | Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors | PFIZER INC | 2004-07-08 | — | — | US | disclosed |
| US-6710040-B1 | Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors | PFIZER INC. | 2004-03-23 | — | — | US | disclosed |
| WO-2003101958-A2 | FLOURINATED CYCLIC AMIDES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-12-11 | — | — | WO | disclosed |