SCHEMBL8953328

SCHEMBL8953328

CCc1nc(-c2ccccc2)c(C)c(-c2ccc(F)cc2)c1C=CP(=O)(C[C@H](CC(=O)O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)OC

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8953306 1.00 CTSA (0.32) CTSA
SCHEMBL8952769 0.90 ESR1 (0.39)
SCHEMBL8952778 0.90 ESR1 (0.39)
SCHEMBL8952917 0.89 NR1I2 (0.41)
SCHEMBL8953217 0.85 ESR1 (0.41)
SCHEMBL8953196 0.85 ESR1 (0.41)
SCHEMBL8953114 0.85
SCHEMBL8953132 0.85
SCHEMBL8952719 0.82
SCHEMBL9562809 0.81 HMGCR (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506219-A ANTICHOLESTEROL AND ANTILIPEMIC AGENTS E. R. SQUIBB & SONS, INC. (US) 1996-04-09 US disclosed