Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.56 |
| ▸ | PPARA | Q07869 | 9/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468365 | 0.84 | AKR1B1 (0.43) | PPARGPPARAACESMN1; SMN2SRR | |
| SCHEMBL30759409 | 0.81 | PPARG (0.51) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10170670 | 0.81 | PPARG (0.51) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3351318 | 0.81 | PPARG (0.51) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1822200 | 0.81 | PPARG (0.51) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8953481 | 0.81 | PPARG (0.51) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8953568 | 0.80 | CYP1A2 (0.45) | PPARGPPARAALDH1A1KMT2A | |
| SCHEMBL28019866 | 0.77 | ALDH1A1 (0.49) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28019865 | 0.77 | ALDH1A1 (0.49) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28020287 | 0.77 | ALDH1A1 (0.49) | PPARGPPARASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514773-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |