Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953782 | 0.90 | MAOB (0.40) | ALOX5MAOBKMT2APPARARXRA | |
| SCHEMBL8953777 | 0.87 | MAOB (0.43) | MAOBKMT2ANR4A2 | |
| SCHEMBL8953702 | 0.87 | MAOB (0.43) | MAOBKMT2ANR4A2 | |
| SCHEMBL8953842 | 0.82 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL8953666 | 0.79 | ALOX5 (0.37) | ALOX5MAOBPPARARXRANR1H2 | |
| SCHEMBL8953670 | 0.79 | ALOX5 (0.37) | ALOX5MAOBPPARARXRANR1H2 | |
| SCHEMBL8953864 | 0.78 | MAOB (0.47) | MAOBKMT2ANR4A2 | |
| SCHEMBL8953917 | 0.78 | ALOX5 (0.38) | ALOX5MAOBRXRANR1H2NR1H3 | |
| SCHEMBL8953821 | 0.78 | POLB (0.38) | ALOX5MAOBKMT2ARXRANR1H2 | |
| SCHEMBL8953916 | 0.76 | ALOX5 (0.37) | ALOX5MAOBRXRANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |