Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930363 | 1.00 | POLB (0.50) | POLBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL28334041 | 1.00 | POLB (0.50) | POLBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL11741292 | 0.98 | POLB (0.49) | POLBTDP1MEN1KMT2ANPC1 | |
| P-Xylene SCHEMBL28193363 | 0.92 | P4HTM (0.49) | POLBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL27815495 | 0.92 | POLB (0.45) | POLBTDP1MEN1KMT2ANPC1 | |
| O-Xylene SCHEMBL28193365 | 0.88 | MEN1 (0.53) | POLBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL2031774 | 0.88 | POLB (0.42) | POLBTDP1MEN1KMT2ANPC1 | |
| Potassium Ion SCHEMBL28215224 | 0.88 | HCAR2 (0.43) | POLBTDP1MEN1KMT2ANPC1 | |
| Pyrazinoic Acid SCHEMBL22119726 | 0.87 | KDM4E (0.71) | POLBTDP1MEN1KMT2ANPC1 | |
| Benzoic Acid SCHEMBL28285935 | 0.87 | MEN1 (0.51) | POLBTDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2312 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | claimed |
| CN-118703414-B | Strain for producing 5-methylpyrazine 2 carboxylic acid and construction method and application thereof | 天津工微生物科技有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118745157-A | Preparation method of acipimox | 四川豪运药业股份有限公司 | 2024-10-08 | — | — | CN | claimed |
| CN-118703414-A | Strain for producing 5-methylpyrazine 2 carboxylic acid and construction method and application thereof | 天津工微生物科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-117965239-A | Preparation method of solid aroma-diving substance and aroma-diving type cigarette lap adhesive | 河南中烟工业有限责任公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117865976-A | Cimicin derivative, preparation method and medicinal application thereof | 吉林农业大学 | 2024-04-12 | — | — | CN | claimed |
| CN-113929632-B | Acipimox calcium salt and preparation method thereof | 鲁南制药集团股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-115477760-B | Polyglycol modified iodine-doped coordination polymer, preparation method thereof, suspension and light modulation device | 江苏集萃智能液晶科技有限公司 | 2023-11-17 | — | — | CN | claimed |
| EP-0730597-A1 | HETEROCYCLIC ESTERS OF RAPAMYCIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-11 | — | — | EP | claimed |
| US-5516906-A | Process for the preparation of N-[2-[4-(aminosulfonyl) phenyl]ethyl]5-methylpyrazinecarboxamide | USV LIMITED (IN) | 1996-05-14 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0673783-A2 | Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1995014697-A1 | HETEROCYCLIC ESTERS OF RAPAMYCIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-01 | — | — | WO | claimed |
| US-5385909-A | Heterocyclic esters of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| EP-0316945-B1 | ELECTROCHEMICAL SYNTHESIS OF 2-METHYL-5-PYRAZINOIC ACID | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1992-04-08 | — | — | EP | claimed |
| US-5091066-A | ELECTROCHEMICAL SYNTHESIS OF 2-METHYL-5-PYRAZINOIC ACID | PRESIDENZA DEL CONSIGLIO DEI MINISTRI (IT) | 1992-02-25 | — | — | US | claimed |
| EP-0466042-A2 | Microbiological process for the oxidation of methyl groups | LONZA AG (CH) | 1992-01-15 | — | — | EP | claimed |
| EP-0316945-A1 | Electrochemical synthesis of 2-methyl-5-pyrazinoic acid | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1989-05-24 | — | — | EP | claimed |