Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391681 | 0.91 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL1996999 | 0.80 | APP (0.73) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2628260 | 0.80 | APP (0.73) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL3185914 | 0.80 | APP (0.60) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL12422438 | 0.78 | APP (0.66) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL10311768 | 0.78 | RORC (0.71) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2628245 | 0.76 | RORC (0.68) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL11973310 | 0.76 | APP (0.63) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL5528929 | 0.76 | MAPT (0.70) | APPMAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL25027905 | 0.76 | APP (0.63) | APPGLAGAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1586-H | Methods of and systems for encoding and decoding a beam of light utilizing nonlinear organic signal processors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1996-09-03 | — | — | US | claimed |
| US-H1586-H | Methods of and systems for encoding and decoding a beam of light utilizing nonlinear organic signal processors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1996-09-03 | — | — | US | disclosed |