Sugi Predict

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SCHEMBL8954680

SCHEMBL8954680

N#Cc1cccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCC(C(=O)O)C3CCCCC32)c1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 14/20 0.58
▸ PLG P00747 6/20 0.49
▸ ST14 Q9Y5Y6 4/20 0.48
▸ HPN P05981 1/20 0.48
▸ HGFAC Q04756 1/20 0.48
▸ PLAU P00749 5/20 0.48
▸ F2 P00734 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954702 0.92 F10 (0.56) F10PLGHPNPLAUF2
SCHEMBL8954781 0.89 F10 (0.64) F10PLGST14HPNHGFAC
SCHEMBL8954813 0.89 F10 (0.63) F10PLGST14HPNHGFAC
SCHEMBL8954873 0.86 F10 (0.80) F10PLGST14HPNHGFAC
Iodide SCHEMBL8954861 0.85 F10 (0.78) F10PLGST14HPNHGFAC
Iodide SCHEMBL8955094 0.84 F10 (0.61) F10PLGST14HPNHGFAC
SCHEMBL7566084 0.80 MMP2 (0.58) F10PLGST14HPNHGFAC
SCHEMBL18049375 0.80 MMP2 (0.58) F10PLGST14HPNHGFAC
SCHEMBL18049404 0.80 PLG (0.63) F10PLGST14HPNHGFAC
SCHEMBL19923046 0.80 PLG (0.63) F10PLGST14HPNHGFAC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518735-A ANTICOAGULANTS ADMINISTERED BY MOUTH PENTAPHARM AG (CH) 1996-05-21 — — US disclosed
WO-1992008709-A1 META-SUBSTITUTED PHENYL ALANINE DERIVATIVES PENTAPHARM AG (CH) 1992-05-29 — — WO disclosed