Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 5/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9666014 | 0.81 | F10 (0.49) | F10F2PRSS1PLGPROC | |
| SCHEMBL8954753 | 0.79 | F2 (0.65) | F10F2PLGPLAUST14 | |
| SCHEMBL8954844 | 0.78 | F10 (0.50) | F10F2PRSS1PLGPROC | |
| SCHEMBL8954943 | 0.77 | F10 (0.49) | F10F2PLGPROCPLAU | |
| SCHEMBL8954673 | 0.77 | F10 (0.43) | F10F2PRSS1PLGPROC | |
| Bicarbonate SCHEMBL9665131 | 0.77 | F10 (0.57) | F10F2PRSS1PLGPLAU | |
| Hydrochloric Acid SCHEMBL8954922 | 0.76 | F10 (0.51) | F10F2PRSS1PLGPROC | |
| SCHEMBL8954706 | 0.76 | F10 (0.52) | F10F2PLGPROCPLAU | |
| SCHEMBL8954839 | 0.76 | F10 (0.47) | F10F2PLGPROCPLAU | |
| SCHEMBL8954806 | 0.75 | F10 (0.52) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |