Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 8/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PROC | P04070 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9663503 | 0.92 | F10 (0.41) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8954736 | 0.91 | F10 (0.40) | F10F2PRSS1PLGPLAU | |
| Hydrochloric Acid SCHEMBL8954790 | 0.90 | F10 (0.40) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8954791 | 0.88 | ABCB1 (0.34) | — | |
| SCHEMBL8954757 | 0.86 | KAT6A (0.35) | — | |
| SCHEMBL8954860 | 0.81 | F10 (0.41) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8954760 | 0.69 | F10 (0.48) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8954673 | 0.68 | F10 (0.43) | F10F2PRSS1PLGPLAU | |
| Bicarbonate SCHEMBL9665131 | 0.68 | F10 (0.57) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8954743 | 0.67 | F10 (0.40) | F10F2PRSS1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |