SCHEMBL8955102

SCHEMBL8955102

CCCCSc1ccc2cc3c(cc2c1)C(=N)NC3=N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.41
AR P10275 2/20 0.40
XDH P47989 1/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
CYP2C9 P11712 5/20 0.36
CYP2C19 P33261 5/20 0.36
CYP3A4 P08684 4/20 0.36
CYSLTR2 Q9NS75 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
TLR8 Q9NR97 1/20 0.35
BACE1 P56817 1/20 0.35
CYP1A2 P05177 4/20 0.35
CYP2E1 P05181 3/20 0.35
CYP2C8 P10632 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2B6 P20813 3/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7815633 0.88 AR (0.41) CNR2ARXDHMAOAMAOB
SCHEMBL8638831 0.82 AR (0.51) CNR2ARXDHMAOAMAOB
SCHEMBL20456891 0.77 CNR2 (0.45) CNR2ARXDHMAOAMAOB
SCHEMBL31038416 0.77 CNR2 (0.45) CNR2ARXDHMAOAMAOB
SCHEMBL9513855 0.77 MAOA (0.31) MAOAMAOB
SCHEMBL9364534 0.76 AR (0.44) CNR2ARXDHMAOAMAOB
SCHEMBL30417613 0.75 CNR2 (0.59) CNR2ARXDHMAOAMAOB
SCHEMBL423417 0.75 CNR2 (0.59) CNR2ARXDHMAOAMAOB
SCHEMBL8955587 0.73 AR (0.64) CNR2ARXDHMAOAMAOB
SCHEMBL19058100 0.72 NPC1 (0.50) CNR2ARMAOAMAOBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484685-A Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI, LTD. (JP) 1996-01-16 US disclosed
EP-0366440-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed