Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955175 | 1.00 | CTSC (0.46) | CTSCMMENOS1ALPIPKM | |
| SCHEMBL825577 | 0.81 | MME (0.67) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL30581391 | 0.81 | MME (0.67) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL1329567 | 0.81 | MME (0.67) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL5065345 | 0.81 | MME (0.67) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL7355800 | 0.81 | MME (0.67) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL30581399 | 0.81 | MME (0.67) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL8082492 | 0.78 | MME (0.63) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL14772130 | 0.78 | MME (0.63) | CTSCMMEALPIPKMPTGS1 | |
| SCHEMBL30862466 | 0.78 | MME (0.63) | CTSCMMEALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581899-A4 | IMPROVED PROCESS FOR THE PREPARATION OF 1S-(1R*, 2S*, 3R*))-N-(4-(MORPHOLINYLSULFONYL)-L-PHENYLALANYL-3-(2-AMINO-4-THIAZOLYL)-N- (1-CYCLOHEXYLMETHYL)-2,3-DIHYDROXY-5-METHYLHEXYL)-L-ALANINAMIDE | WARNER LAMBERT CO (US) | 1996-10-02 | — | — | EP | disclosed |