SCHEMBL5065345

SCHEMBL5065345

N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.67
ALPI P09923 1/20 0.62
PKM P14618 1/20 0.62
PTGS1 P23219 1/20 0.62
XIAP P98170 1/20 0.62
SLC7A5 Q01650 1/20 0.62
CTSC P53634 1/20 0.61
ACE P12821 4/20 0.60
CPA1 P15085 4/20 0.60
ACE2 Q9BYF1 4/20 0.60
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30581399 1.00 MME (0.67) MMEALPIPKMPTGS1XIAP
SCHEMBL30581391 1.00 MME (0.67) MMEALPIPKMPTGS1XIAP
SCHEMBL1329567 1.00 MME (0.67) MMEALPIPKMPTGS1XIAP
SCHEMBL825577 1.00 MME (0.67) MMEALPIPKMPTGS1XIAP
SCHEMBL7355800 1.00 MME (0.67) MMEALPIPKMPTGS1XIAP
SCHEMBL14772130 0.97 MME (0.63) MMEALPIPKMPTGS1XIAP
SCHEMBL30862466 0.97 MME (0.63) MMEALPIPKMPTGS1XIAP
SCHEMBL30862442 0.97 MME (0.63) MMEALPIPKMPTGS1XIAP
SCHEMBL8082487 0.97 MME (0.63) MMEALPIPKMPTGS1XIAP
SCHEMBL8082492 0.97 MME (0.63) MMEALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899240-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-04-29 CN claimed
CN-119390765-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-02-07 CN claimed
CN-118772231-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2024-10-15 CN claimed
WO-2024163598-A2 PEPTIDES COMPRISING THIOESTER GROUPS, INCLUDING DEPSIPEPTIDE THIOESTERS, METHODS OF MAKING, AND USE THEREOF BRANDEIS UNIVERSITY (US) 2024-08-08 WO claimed
US-3965260-A Anti-inflammatory dipeptide McArthur, John N. (CA) 1976-06-22 US claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 EP disclosed
EP-4621826-A1 METHOD FOR DETECTING NON-RACEMIC MIXTURES USING COLD ION PHOTOFRAGMENTATION MASS SPECTROMETRY ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2025-09-24 EP disclosed
US-20250186427-A1 METHODS AND COMPOSITIONS FOR TREATING VASOMOTOR SYMPTOMS UNIVERSITY OF WASHINGTON 2025-06-12 US disclosed
CN-119899240-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-04-29 CN disclosed
CN-119390765-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-02-07 CN disclosed
US-20250011362-A1 COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF CANCER Clarity Pharmaceuticals Limited (AU) 2025-01-09 US disclosed
US-20220125781-A1 Methods and Compositions for Treating Vasomotor Symptoms UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2022-04-28 US disclosed
WO-2022074228-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS MC2 THERAPEUTICS LTD (GB) 2022-04-14 WO disclosed
US-20220089646-A1 A CYCLIC PEPTIDE THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-24 US disclosed
US-20080255033-A1 Metallopeptide gamma-Melanocyte Stimulating Hormone Compounds PALATIN TECHNOLOGIES, INC. (US) 2008-10-16 US disclosed
US-7385025-B2 Metallopeptide compounds PALATIN TECHNOLOGIES, INC. (US) 2008-06-10 US disclosed
US-20050282739-A1 Metallopeptide compounds PALATIN TECHNOLOGIES, INC. (US) 2005-12-22 US disclosed
US-20040248212-A1 Knockout identification of target-specific sites in peptides PALATIN TECHNOLOGIES, INC. (US) 2004-12-09 US disclosed
US-3965260-A Anti-inflammatory dipeptide McArthur, John N. (CA) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP MME 824/4885ALPI 1473/4885PKM 1219/4885
US-20220089646-A1 A CYCLIC PEPTIDE VIP, CALCA, CALCB MME 273/4885ALPI 2058/4885PKM 3810/4885
US-20080255033-A1 Metallopeptide gamma-Melanocyte Stimulating Hormone Compounds MC1R, NGLY1, HM13 MME 277/4885ALPI 2453/4885PKM 4677/4885
US-20250186427-A1 METHODS AND COMPOSITIONS FOR TREATING VASOMOTOR SYMPTOMS VASP, PDE3A, PDE2A MME 1103/4885ALPI 1924/4885PKM 1061/4885
US-20250011362-A1 COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF CANCER FOLH1, PSMA2, PSMA3 MME 184/4885ALPI 533/4885PKM 1232/4885
US-20050282739-A1 Metallopeptide compounds MC1R, HM13, MC3R MME 127/4885ALPI 2381/4885PKM 4736/4885
US-20220125781-A1 Methods and Compositions for Treating Vasomotor Symptoms VASP, PDE3A, PDE2A MME 1103/4885ALPI 1924/4885PKM 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.