Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.55 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27589883 | 1.00 | PRSS1 (0.55) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| SCHEMBL4514316 | 0.96 | SIRT2 (0.55) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| SCHEMBL28339600 | 0.96 | SIRT2 (0.55) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| Hydrochloric Acid SCHEMBL7692288 | 0.95 | SIRT2 (0.54) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| Hydrochloric Acid SCHEMBL8783156 | 0.95 | SIRT2 (0.54) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| SCHEMBL1022361 | 0.91 | PRSS1 (0.52) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| SCHEMBL2670570 | 0.91 | CTSK (0.62) | CTSLCTSSCTSKCTSB | |
| Hydrochloric Acid SCHEMBL7974895 | 0.89 | PPARA (0.53) | PRSS1PRSS2PRSS3TPSAB1SYK | |
| SCHEMBL18354663 | 0.89 | SYK (0.55) | SYKCTSLCTSSITGB3ITGA2B | |
| SCHEMBL7222412 | 0.89 | SYK (0.55) | SYKCTSLCTSSITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164483-A | Synthesis method of Cbz-arginine tert-butyl ester | 吉尔生化（上海）有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-117164483-A | Synthesis method of Cbz-arginine tert-butyl ester | 吉尔生化（上海）有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164483-A | Synthesis method of Cbz-arginine tert-butyl ester | 吉尔生化（上海）有限公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-0707577-A4 | HEME BINDING COMPOUNDS AND USE THEREOF | WISCONSIN MED COLLEGE INC (US) | 1996-11-06 | — | — | EP | disclosed |
| EP-0707577-A1 | HEME BINDING COMPOUNDS AND USE THEREOF | MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995013804-A1 | S-ALKYL-ISOTHIOUREIDO-AMINO ACIDS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-05-26 | — | — | WO | disclosed |
| WO-1995001972-A1 | HEME BINDING COMPOUNDS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-01-19 | — | — | WO | disclosed |
| US-5364881-A | S-alkyl-isothioureido-amino acids and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1994-11-15 | — | — | US | disclosed |