Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958295 | 0.89 | HPGD (0.41) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL12227894 | 0.85 | KDM4E (0.49) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL12227892 | 0.85 | KDM4E (0.49) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL276599 | 0.85 | KDM4E (0.41) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL23028315 | 0.81 | ALDH1A1 (0.38) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL12541603 | 0.79 | MEN1 (0.52) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL22504633 | 0.78 | ALDH1A1 (0.36) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL12145826 | 0.77 | SMN1; SMN2 (0.55) | KDM4EHPGDALDH1A1POLBMEN1 | |
| SCHEMBL14220714 | 0.77 | NPC1 (0.52) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL19188818 | 0.75 | KDM4E (0.43) | KDM4EHPGDALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8193055-A | — | — | None | — | — | JP | disclosed |
| JP-H08193055-A | 2,6-BIS(2-T-BUTOXYCARBONYLMETHYLOXYPHENYLMETHYL)-1-T-BUTOXYCARBONYLMETHYLOXY-4-METHYLBENZENE AND ITS DERIVATIVE | SHIN ETSU CHEM CO LTD | 1996-07-30 | — | — | JP | disclosed |