Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926658 | 0.90 | PLA2G2A (0.59) | PLA2G2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL9697417 | 0.84 | NR5A1 (0.56) | PLA2G2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL8778575 | 0.83 | PLA2G2A (0.49) | PLA2G2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL5226337 | 0.81 | PLA2G2A (0.82) | PLA2G2AALDH1A1HPGDBLMTP53 | |
| SCHEMBL8956013 | 0.81 | TP53 (0.54) | PLA2G2AALDH1A1NR5A1CNR1CNR2 | |
| SCHEMBL8956129 | 0.81 | CNR2 (0.53) | PLA2G2ANR5A1CNR1CNR2BLM | |
| SCHEMBL16962164 | 0.81 | PLA2G2A (0.43) | PLA2G2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL593989 | 0.81 | PLA2G2A (0.50) | PLA2G2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL5223955 | 0.80 | PLA2G2A (0.61) | PLA2G2AALDH1A1HPGDKDM4EHTT | |
| SCHEMBL16951369 | 0.80 | PLA2G2A (0.49) | PLA2G2AALDH1A1HPGDKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |