Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 11/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PROC | P04070 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954914 | 0.92 | PLG (0.44) | PLGF10HPNF2PLAU | |
| SCHEMBL8954990 | 0.88 | PLG (0.46) | PLGF10HPNF2PLAU | |
| SCHEMBL7058121 | 0.72 | PLG (0.43) | PLGF10HPNF2PLAU | |
| SCHEMBL9665229 | 0.71 | F2 (0.64) | PLGF10HPNF2PLAU | |
| SCHEMBL8954934 | 0.66 | F2 (0.76) | PLGF10HPNF2PLAU | |
| SCHEMBL29682629 | 0.66 | PLG (0.62) | PLGF10HPNF2PLAU | |
| SCHEMBL18049398 | 0.65 | PLG (0.62) | PLGF10HPNF2PLAU | |
| SCHEMBL18049397 | 0.65 | PLG (0.62) | PLGF10HPNF2PLAU | |
| SCHEMBL8954649 | 0.64 | F2 (0.60) | PLGF10HPNF2PLAU | |
| SCHEMBL6162909 | 0.64 | MAPK1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |