Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 12/20 | 0.43 |
| ▸ | F10 | P00742 | 8/20 | 0.43 |
| ▸ | HPN | P05981 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PROC | P04070 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954061 | 0.85 | PLAU (0.52) | PLGF10HPNPLAUF2 | |
| Hydrochloric Acid SCHEMBL250043 | 0.84 | PLAU (0.51) | PLGF10HPNPLAUF2 | |
| SCHEMBL7585899 | 0.75 | PLG (0.43) | PLGF10HPNPLAUF2 | |
| Hydrochloric Acid SCHEMBL7584788 | 0.74 | PLG (0.43) | PLGF10HPNPLAUF2 | |
| SCHEMBL2953288 | 0.74 | PLAU (0.48) | PLGF10HPNPLAUF2 | |
| Hydrochloric Acid SCHEMBL4451933 | 0.74 | PLAU (0.48) | PLGF10HPNPLAUF2 | |
| SCHEMBL8954990 | 0.73 | PLG (0.46) | PLGF10HPNPLAUF2 | |
| SCHEMBL8955632 | 0.72 | PLG (0.44) | PLGF10HPNPLAUF2 | |
| SCHEMBL8954914 | 0.72 | PLG (0.44) | PLGF10HPNPLAUF2 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL7112283 | 0.66 | KMT2A (0.42) | PLGF10HPNPLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264828-B1 | Inhibitor of urokinase | WILEX AG (DE) | 2004-04-14 | — | — | EP | disclosed |
| EP-1098651-B1 | NOVEL UROKINASE INHIBITORS | WILEX AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1264828-A1 | New inhibitor of urokinase | Wilex AG (DE) | 2002-12-11 | — | — | EP | disclosed |
| EP-0635008-B1 | PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS | PENTAPHARM AG (CH) | 2002-09-04 | — | — | EP | disclosed |