Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087900 | 1.00 | CHRNB2 (0.61) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL31087905 | 1.00 | CHRNB2 (0.61) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL31087898 | 0.98 | CHRNB2 (0.62) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL5518334 | 0.98 | CHRNB2 (0.62) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL29832812 | 0.94 | CHRNB2 (0.64) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL5523744 | 0.94 | CHRNB2 (0.64) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL14028449 | 0.92 | CHRNB2 (0.69) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL77341 | 0.89 | CHRNB2 (0.66) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL3977089 | 0.88 | CHRNB2 (0.64) | CHRNB2CHRNA4HPGDLMNAMEN1 | |
| SCHEMBL15498199 | 0.85 | CHRNB2 (0.73) | CHRNB2CHRNA4HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |