SCHEMBL8955802

SCHEMBL8955802

C/C=C/C1OCC(c2ccc(-c3ccc(-c4ccc(OCCCCCCC)c(F)c4F)cc3)cc2F)CO1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.35
PTPN11 Q06124 5/20 0.33
PTPN1 P18031 1/20 0.32
PTPN6 P29350 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955717 1.00 FPR2 (0.35) FPR2PTPN11PTPN1PTPN6THRA
SCHEMBL8955860 1.00 FPR2 (0.35) FPR2PTPN11PTPN1PTPN6THRA
SCHEMBL8955818 1.00 FPR2 (0.35) FPR2PTPN11PTPN1PTPN6THRA
SCHEMBL8955804 0.99 FPR2 (0.35) FPR2PTPN11PTPN1PTPN6
SCHEMBL8955914 0.96 FPR2 (0.32) FPR2
SCHEMBL8955919 0.94 FPR2 (0.36) FPR2
SCHEMBL8957779 0.92 FPR2 (0.35) FPR2PTPN11
SCHEMBL8957778 0.92 FPR2 (0.35) FPR2PTPN11
SCHEMBL8957766 0.92 FPR2 (0.35) FPR2PTPN11
SCHEMBL8957762 0.92 FPR2 (0.35) FPR2PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed