Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340540 | 0.91 | ALDH1A1 (0.50) | CNR1CNR2FFAR1PPARGPPARD | |
| SCHEMBL8956129 | 0.90 | CNR2 (0.53) | CNR1CNR2PLA2G2AAHR | |
| Floverine SCHEMBL2109150 | 0.85 | ALDH1A1 (0.52) | CNR1CNR2ALDH1A1MAPK1AHR | |
| SCHEMBL1573275 | 0.85 | ALDH1A1 (0.52) | CNR1CNR2ALDH1A1MAPK1AHR | |
| SCHEMBL13095985 | 0.84 | TP53 (0.51) | CNR1CNR2FFAR1PPARGPPARD | |
| SCHEMBL15519746 | 0.83 | MAPT (0.51) | ALDH1A1TSHR | |
| SCHEMBL9688133 | 0.83 | MAPT (0.51) | ALDH1A1TSHR | |
| SCHEMBL8755478 | 0.83 | MAPT (0.51) | ALDH1A1TSHR | |
| SCHEMBL1006059 | 0.83 | MAPT (0.51) | ALDH1A1TSHR | |
| SCHEMBL14831278 | 0.82 | ALDH1A1 (0.41) | CNR1CNR2FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |