Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956263 | 0.91 | TSHR (0.45) | TSHRCA2CA1THRBCYP3A4 | |
| SCHEMBL8956211 | 0.91 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL6858408 | 0.86 | TSHR (0.52) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL6670156 | 0.85 | TSHR (0.40) | TSHRCA2CA1THRBCYP3A4 | |
| SCHEMBL11057147 | 0.82 | TSHR (0.47) | TSHRCA2LMNA | |
| SCHEMBL6668662 | 0.82 | TSHR (0.47) | TSHRCA2CA1THRBCYP3A4 | |
| SCHEMBL6553011 | 0.81 | TSHR (0.42) | TSHRCA2CA1THRBCYP3A4 | |
| SCHEMBL8955893 | 0.81 | TSHR (0.50) | TSHRCA2CA1THRBCYP3A4 | |
| SCHEMBL22230991 | 0.79 | ALDH1A1 (0.40) | TSHRTHRBTDP1ALDH1A1LMNA | |
| SCHEMBL6669913 | 0.79 | TSHR (0.40) | TSHRCA2CA1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690080-A2 | Hindered-hydroxyl functional (meth) acrylate monomers containing di (meth) acrylates and compositions including same | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-01-03 | — | — | EP | claimed |
| US-5442023-A | Without premature crosslinking or gel formation; curable protective coatings, inks, adhesives | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-08-15 | — | — | US | claimed |
| EP-0690080-A2 | Hindered-hydroxyl functional (meth) acrylate monomers containing di (meth) acrylates and compositions including same | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5442023-A | Without premature crosslinking or gel formation; curable protective coatings, inks, adhesives | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |